"Dr. Yu is a pioneer of targeted RNA editing to correct protein translation defects caused by premature termination codons,” said
Dr. Yu is a professor of biochemistry and biophysics at the
"Targeted RNA editing technology has the potential to develop transformative therapies for genetic conditions," said Dr. Yu. "I look forward to working with ProQR as they continue to develop new therapeutics for patients with rare diseases that do not currently have treatment options."
About Axiomer® Technology Platform
ProQR is pioneering a next-generation RNA technology called Axiomer®, which could potentially yield a new class of medicines for genetic diseases. Axiomer® “Editing Oligonucleotides”, or EONs, mediate single nucleotide changes to RNA in a highly specific and targeted way using molecular machinery that is present in human cells. The Axiomer® EONs are designed to recruit an endogenously expressed RNA editing system called ADAR, which it can direct to the change of an Adenosine (A) to an Inosine (I) in the RNA – an Inosine is translated as a Guanosine (G).
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Source: ProQR Therapeutics N.V.